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My daughter with autism was taken off risperdal at the end of march.

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risperdal has low to moderate affinity ki of 47 to 253 nm for the serotonin 5ht1c, 5ht1d, and 5ht1a receptors, weak affinity ki of 620 to 800 nm for the dopamine d1 and haloperidol-sensitive sigma site, and no affinity when tested at concentrations 10 -5 m for cholinergic muscarinic or 1 and 2 adrenergic receptors.

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the efficacy of risperdal in the treatment of irritability associated with autistic disorder was established in two 8-week, placebo-controlled trials in children and adolescents aged 5 to 16 years who met the dsm-iv criteria for autistic disorder.

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risperdal is also used to treat symptoms of irritability in autistic children who are 5 to 16 years old.

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in may 2011, the company recently set aside an unspecified amount to settle federal cases of improper marketing of risperdal.

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